Neutron capture therapy with boron in the treatment of glioblastoma multiforme.
نویسندگان
چکیده
منابع مشابه
Folate Functionalized Boron Nitride Nanotubes and their Selective Uptake by Glioblastoma Multiforme Cells: Implications for their Use as Boron Carriers in Clinical Boron Neutron Capture Therapy
Boron neutron capture therapy (BNCT) is increasingly being used in the treatment of several aggressive cancers, including cerebral glioblastoma multiforme. The main requirement for this therapy is selective targeting of tumor cells by sufficient quantities of (10)B atoms required for their capture/irradiation with low-energy thermal neutrons. The low content of boron targeting species in gliobl...
متن کاملInvestigation the potential of Boron neutron capture therapy (BNCT) to treat the lung cancer
Introduction: Boron neutron capture therapy (BNCT) is recommended to treat the glioblastoma tumor. It is well known that neuron beams are more effective treatment than photon beams to treat hypoxia tumors due to interaction of neutron with nucleus and production of heavy particles such as 7Li and alpha particle. In this study to evaluate the suitability of BNCT for treating of ...
متن کاملPatient positioning in static beams for boron neutron capture therapy of malignant glioma.
PURPOSE To develop a procedure for the optimum patient positioning and immobilization during boron neutron capture therapy (BNCT) of glioblastoma multiforme (GBM) at the Brookhaven medical research reactor (BMRR). METHODS A replica of the treatment room in the BMRR was constructed to simulate patient position. A unique feature is a transparent opening in wall to simulate the location of the b...
متن کاملMonte Carlo based treatment planning systems for Boron Neutron Capture Therapy in Petten, The Netherlands
Boron Neutron Capture Therapy (BNCT) is a bimodal form of radiotherapy for the treatment of tumour lesions. Since the cancer cells in the treatment volume are targeted with B, a higher dose is given to these cancer cells due to the B(n,α)Li reaction, in comparison with the surrounding healthy cells. In Petten (The Netherlands), at the High Flux Reactor, a specially tailored neutron beam has bee...
متن کامل10B Concentration, Phantom Size and Tumor Location Dependent Dose Enhancement and Neutron Spectra in Boron Neutron Capture Therapy
Background: The amount of average dose enhancement in tumor loaded with 10B may vary due to various factors in boron neutron capture therapy.Objective: This study aims to evaluate dose enhancement in tumor loaded with 10B under influence of various factors and investigate the dependence of this dose enhancement on neutron spectra changes.Material and Methods: In this simulation stud...
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ورودعنوان ژورنال:
- The American journal of roentgenology, radium therapy, and nuclear medicine
دوره 71 2 شماره
صفحات -
تاریخ انتشار 1954